The news magazine of the South Pacific · since 1930

Pacific Islands Monthly, 1 August 1950Vol. XXI, No. 1

Paludrine

p. 41 · Read in the full issue

And Its Effect On Malaria

From Our Own Correspondent

Honiara, July 12.

MEDICAL opinion in the British Solo mon Islands disagrees with the ar ticle regarding Paludrine, in the May issue of the PIM. It was said that the drug’s effectiveness as an anti-malarial drug was said to be decreasing.

Medical officers here consider that the immunity which the malaria parasite can develop to paludrine is relative; the para site may be able to resist small doses of Paludrine, but cannot easily survive the prophylactic dose of one tablet per day which is prescribed at present.

Sir Henry Coveil, a word-wide au thority on malaria, states that on a rou tine of one tablet per day, Malignant Tertian Malaria (which is the killer) cannot break through.

BSIP medical opinion is that, if heavy infection takes place, through the bites of large numbers of infected mosquitoes, Benign Tertian Malaria can on occa sions pierce the Paludrine defences.

Paludrine, however, is still considered the best anti-malarial drug available; being a true prophylactic against Malig nant Tertian Malaria and usually an ef ficient suppressive against Benign Ter tian.